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Causes, Signs and Symptoms
Causes
An allergic reaction to medication is caused by an immune system response, usually to modified proteins in the drug. Severe allergic reaction occurs when the immune system produces an antibody called immunoglobulin E (IgE). This antibody binds to cells in the body (called mast cells) and causes the release of histamine (substance that dilates blood vessels) and other chemicals. Common drugs that may cause an allergic reaction include the following: Antibiotics (e.g., penicill...Read the full article 
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